Although they have the same common name, this moonflower vine (Ipomoea alba) is not the same as Datura. Datura blossoms have a deep trumpet shape and bloom in the daytime and at night. Datura is very toxic, while it’s only the seeds of moonflower vines that have a mild hallucinogenic effect.
Since moonflower seeds are mildly toxic to humans and pets, use caution when planting them and remove the spent flowers before they go to seed.

Moonflowers are photo-sensitive and start to open their flowers at night as the sun goes down close again as the sun comes up. They may, however, stay open during very cloudy days with little sunlight.

Moonflower can become invasive in tropical and subtropical locations where conditions allow it to grow continually. However, in colder climates, moonflower will die off during the winter. Moonflower, when allowed to self-seed, can return the following season.

Allow the moonflower plant to die and begin drying out. Once the flowers droop, remove a seed pod from the base of the flower and shake the pod. If the seeds inside make a rattling sound, they’ll be ready to harvest. Pull the seed pods off the vine. Crush the pod in your hand and separate the large white seeds. Allow the seeds to fully dry, then store in a cool, dark location to plant again another season.